It generally depends on the type of pest to be controlled and the size of your home. As an example an initial service for ants will routinely take between 30 and 45 minutes to complete. If you sign up for a maintanance service each application will usually take around 20 minutes. A treatment for subterranean termites can take anywhere from one hour to two days to complete. A fumigation for drywood termites will require the home to be completely vacated for two days.